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Atomic structures of oxymyoglobin and oxyhaemoglobin and the cooperative mechanism of oxygen binding

✍ Scribed by M.F. Perutz


Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
234 KB
Volume
79
Category
Article
ISSN
0020-1693

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## Abstract Analysis of experimental equilibrium constants for the oxygenation of hemoglobin leads to a plausible mechanism for the effect of pH and of chloride ions on cooperativity in hemoglobin. According to this mechanism, the structural changes responsible for cooperativity in chloride‐ and 2,