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Atomic-Resolution Imaging in Liquids : FM-AFM as a Tool for Measuring Biological Samples in Native Environment

✍ Scribed by Bart W. Hoogenboom


Publisher
Wiley (John Wiley & Sons)
Year
2006
Weight
657 KB
Volume
8
Category
Article
ISSN
1439-4243

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✦ Synopsis


Atomic force microscopy (AFM) is the only available experimental technique to image individual biological molecules in liquid environment with subnanometer resolution. Recently, a frequency-modulation (FM) technique has been used to enhance the resolution of AFM in liquid, resulting in images showing atomic resolution and atomic-scale defects ("true atomic resolution''). FM-AFM also allows to better control the imaging conditions and the applied forces than conventional modes of operation of AFM in liquid.