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Atomic force microscopy evidence for conformational changes of fibronectin adsorbed on unmodified and sulfonated polystyrene surfaces

✍ Scribed by Hanna M. Kowalczyńska; Robert Kołos; Małgorzata Nowak-Wyrzykowska; Jacek Dobkowski; Danek Elbaum; Andrzej Szczepankiewicz; Jarosław Kamiński


Book ID
118284154
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
488 KB
Volume
91A
Category
Article
ISSN
1549-3296

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✍ Bergkvist, Magnus ;Carlsson, Jan ;Oscarsson, Sven 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 235 KB

## Abstract Human plasma fibronectin (Fn) is a large flexible protein stabilized by intermolecular ionic interactions forming a compact structure. On altering solution conditions, the structure can revert to a more expanded state, thereby exposing previously hidden domains (e.g., cell‐binding sites