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Atomic Force Microscope Studies on Condensation of Plasmid DNA with Functionalized Fullerenes

✍ Scribed by Hiroyuki Isobe; Sho Sugiyama; Ken-ichi Fukui; Yasuhiro Iwasawa; Eiichi Nakamura

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 224 KB
Volume: 40
Category: Article
ISSN: 0044-8249
DOI: 10.1002/1521-3773(20010917)40:18<3364::aid-anie3364>3.0.co;2-s

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✦ Synopsis

A recent paper reported the first example of the use of a carbon cluster as a vector to deliver DNA into mammalian cells. [1, Thus, mixed with the tailor-made tetraminofullerene 1, a plasmid DNA forms micrometer-sized fullerene ± DNA particles as observed by optical microscope, which, after

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