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ATM polymorphism IVS62+60G>A is not associated with disease aggressiveness in prostate cancer

โœ Scribed by Robert E. Lee Browning IV; Hecheng Li; Eric T. Shinohara; Qiuyin Cai; Heidi Chen; Regina Courtney; Carolyn Cao; Wei Zheng; Bo Lu

Book ID
116945677
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
100 KB
Volume
67
Category
Article
ISSN
0090-4295

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A polymorphism in the CYP17 gene is asso
A polymorphism in the CYP17 gene is associated with prostate cancer risk
โœ Andrea Gsur; Gabriele Bernhofer; Sonja Hinteregger; Gerald Haidinger; Georg Scha ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 63 KB ๐Ÿ‘ 2 views

CYP17 encodes the enzyme cytochrome P-450c17โฃ, which mediates both 17โฃ-hydroxylase and 17,20-lyase in the steroid biosynthesis pathway. A polymorphism in the 5 promoter region of the CYP17 gene has been described. Steroid hormones, especially androgens, are believed to play a key role in the etiolog