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ATM and RPA in meiotic chromosome synapsis and recombination

โœ Scribed by Plug, Annemieke W.; Peters, Antoine H.F.M; Xu, Yang; Keegan, Kathleen S.; Hoekstra, Merl F.; Baltimore, David; Boer, Peter de; Ashley, Terry


Book ID
109918952
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
528 KB
Volume
17
Category
Article
ISSN
1061-4036

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In most eukaryotes, homologous chromosomes undergo synapsis during the first meiotic prophase. A consequence of mutations that interfere with the fidelity or completeness of synapsis can be failure in the formation or maintenance of bivalents, resulting in univalent formation at diakinesis and produ