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Athymic mice express a high level of functional γ-chain but greatly reduced levels of α- and β-chain T-cell receptor messages

✍ Scribed by Yoshikai, Yasunobu; Reis, Marciano D.; Mak, Tak W.


Book ID
109747744
Publisher
Nature Publishing Group
Year
1986
Tongue
English
Weight
483 KB
Volume
324
Category
Article
ISSN
0028-0836

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Functional α and β T cell chain receptor
✍ Kenji Kishihara; Yasunobu Yoshikai; Goro Matsuzaki; Tak W. Mak; Kikuo Nomoto 📂 Article 📅 1987 🏛 John Wiley and Sons 🌐 English ⚖ 657 KB

Functional a and p T cell chain receptor messages can be detected in old but not in young athymic mice\* The expression and sequences of T cell antigen receptor (TcR) a and p-chain genes were investigated in the spleens from congenitally athymic (nude) mice. A small number of Thy-1' cells (-7.0%) w