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ATG16L1 Crohn's disease risk stresses the endoplasmic reticulum of Paneth cells

✍ Scribed by Kaser, A.; Blumberg, R. S.


Book ID
127088329
Publisher
BMJ Publishing Group
Year
2013
Tongue
English
Weight
363 KB
Volume
63
Category
Article
ISSN
0017-5749

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Confirmation of the role of ATG16l1 as a
✍ J.R. Fraser Cummings; Rachel Cooney; Saad Pathan; Carl A. Anderson; Jeffrey C. B πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 93 KB

Background: A German genome-wide nonsynonymous single nucleotide polymorphism (nsSNP) association study identified ATG16L1 as a Crohn's disease (CD) susceptibility gene. The association appeared to be confined to the nsSNP rs2241880 and was confirmed in 2 German independent case-control collections