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ATF/CREB site mediated transcriptional activation and p53 dependent repression of the cyclin A promoter

✍ Scribed by Chantal Desdouets; Catherine Ory; Graziella Matesic; Thierry Soussi; Christian Bréchot; Joëlle Sobczak-Thépot


Book ID
115932288
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
662 KB
Volume
385
Category
Article
ISSN
0014-5793

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## Abstract The p27^Kip1^ (p27) cyclin‐dependent kinase inhibitor and c‐Myc oncoprotein play essential roles in control of cell cycle progression and apoptosis. Induction of __p27__ (__CDKN1B__) gene transcription by Forkhead box O proteins such as FOXO3a leads to growth arrest and apoptosis. Previ