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Ataxia–telangiectasia: guidelines for diagnosis and comprehensive care

✍ Scribed by B. Pietrucha; E. Heropolitańska-Pliszka; T. Kmieć; D. Chmielewski; R. Gatti; E. Bernatowska


Book ID
114359105
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
42 KB
Volume
12
Category
Article
ISSN
1090-3798

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Epidemiological studies have suggested that ataxia-telangiectasia (AT) heterozygotes have a predisposition to cancer, especially breast cancer in women. Now, haplotyping can identify heterozygotes for AT mutation (ATM) in AT families, allowing the risk of cancer associated with ATM heterozygosity st