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At once harmful and beneficial: the dual properties of NF-κB

✍ Scribed by Youssef, Sawsan; Steinman, Lawrence


Book ID
109921703
Publisher
Nature Publishing Group
Year
2006
Tongue
English
Weight
744 KB
Volume
7
Category
Article
ISSN
1529-2908

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## Abstract IL‐4 plays a pivotal role in the development of the Th2 cell mediated humoral immune response and causes IgE‐dependent allergic inflammatory diseases. Expression of IL‐4 in differentiated Th2 cells is regulated by transcription factors such as NF‐AT, AP‐1 and NF‐IL6. Recently, increasin