Asynchronous replication of imprinted genes is established in the gametes and maintained during development
β Scribed by Cedar, Howard; Simon, Itamar; Tenzen, Toyoaki; Reubinoff, Benjamin E.; Hillman, Dahlia; McCarrey, John R.
- Book ID
- 109815586
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 186 KB
- Volume
- 401
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/44866
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Monoallelic expression of the imprinted __H19__ and insulinβlike growth factorβ2 (__Igf2__) genes depends on the hypomethylation of the maternal allele and hypermethylation of the paternal allele of the __H19__ upstream region. Previous studies from our laboratory on liver carcinogenesi
cDNA subtraction was employed to uncover differences in gene expression between myeloproliferative polycythaemia vera (PV) and normal haematopoietic precursors. Following cDNA subtraction using mRNAs isolated from PV and normal CD34+/CD33x bone-marrow cells, expression of the tumour suppressor H19 w