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Asymmetry of frameshift mutagenesis during leading and lagging-strand replication in Escherichia coli

✍ Scribed by Damian Gawel; Piotr Jonczyk; Malgorzata Bialoskorska; Roel M. Schaaper; Iwona J. Fijalkowska


Book ID
114070575
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
113 KB
Volume
501
Category
Article
ISSN
0027-5107

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Replication of the colicin E1 plasmid in
✍ Staudenbauer, Walter L. ;Scherzinger, Eberhard ;Lanka, Erich πŸ“‚ Article πŸ“… 1979 πŸ› Springer 🌐 English βš– 722 KB

The replication of the ColEl plasmid was studied in extracts from E. coli dnaG mutants. It was found that the synthesis of the complementary strands of ColEl DNA can be carried out in these extracts in two consecutive steps: (1) synthesis of the leading L strand independent of the dnaG function, and