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Asymmetry in Histone H3 variants and lysine methylation between paternal and maternal chromatin of the early mouse zygote

✍ Scribed by Godfried W. van der Heijden; Jürgen W. Dieker; Alwin A.H.A. Derijck; Sylviane Muller; Jo H.M. Berden; Didi D.M. Braat; Johan van der Vlag; Peter de Boer


Book ID
119327372
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
740 KB
Volume
122
Category
Article
ISSN
0925-4773

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Differential dynamics of histone H3 meth
✍ Konstantin Lepikhov; Jörn Walter 📂 Article 📅 2004 🏛 BioMed Central 🌐 English ⚖ 623 KB

## Background In the mouse zygote the paternal genome undergoes dramatic structural and epigenetic changes. Chromosomes are decondensed, protamines replaced by histones and DNA is rapidly and actively demethylated. The epigenetic asymmetry between parental genomes remains at least until the 2-cell