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Asymmetric α Alkylation of Aldehydes: Efficiency with Elegance

✍ Scribed by Lotfi Tak-Tak; Prof. Dr. Hamid Dhimane; Dr. Peter I. Dalko

Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
218 KB
Volume
50
Category
Article
ISSN
0044-8249

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An Efficient Enantioselective Method for
An Efficient Enantioselective Method for Asymmetric Friedel–Crafts Alkylation of Indoles with α,β-Unsaturated Aldehydes
✍ Liang Hong; Lei Wang; Chao Chen; Bangzhi Zhang; Rui Wang 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 190 KB 👁 2 views

## Abstract magnified image The Lewis base‐Lewis base bifunctional catalytic system has been developed and successfully applied to the asymmetric Friedel–Crafts alkylation of indoles with α,β‐unsaturated aldehydes. The reactions are promoted by chiral diphenylprolinol trimethylsilyl ether in the p