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Asymmetric Total Synthesis of Nigerone.

✍ Scribed by Evan S. DiVirgilio; Elizabeth C. Dugan; Carol A. Mulrooney; Marisa C. Kozlowski


Publisher
John Wiley and Sons
Year
2007
Weight
15 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract An enantioselective synthesis of the chiral bisnaphthopyrone natural product nigerone and its enantiomer, __ent__‐nigerone, has been realized. The use of constrained 2‐naphthol substrates was critical to producing highly functionalized chiral 1,1′‐binaphthols __via__ asymmetric oxidativ

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