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Asymmetric synthesis XXI. Enantioselective reduction of ketones catalyzed by new (4S,5R)-4,5-diphenyl-1,3,2-oxazaborolidine

โœ Scribed by Jiang Yaozhong; Qin Yong; Mi Aiqiao; Huang Zhitang


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
181 KB
Volume
5
Category
Article
ISSN
0957-4166

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Enantioselective reduction of prochiral
โœ Xingshu Li; Rugang Xie ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 175 KB

Two new optically active l~-amino alcohols 1 and 2 were prepared from Lcystine. The in situ formed chiral oxazaborolidines have been used in the enantioselective catalytic homogeneous borane reduction of prochiral ketones and diketones. The chiral secondary alcohols are obtained with moderate to goo