✦ LIBER ✦
Asymmetric synthesis using α,β-unsaturated sulfoxides. Creation of both (R)- and (S)-asymmetric centers from a single chiral origin.
✍ Scribed by Gen-ichi Tsuchihashi; Shuichi Mitamura; Katsuyuki Ogura
- Book ID
- 104225599
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- French
- Weight
- 245 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
We previously reported that the Michael addltlon of dlethyl malonate to (+)-(R)-tm-B-styryl p-tolyl sulfoxide [(+)-I] In a usual condltlon (EtONa/ EtOH) resulted In the dominant formation of IIIa wrth respect to its diastereomer IIIb.