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Asymmetric Synthesis of α-Amino Phosphonic Acids by Diastereoselective Addition of Trimethyl Phosphite onto Chiral Oxazolidines 1

✍ Scribed by Maury, Catherine; Gharbaoui, Tawfik; Royer, Jacques; Husson, Henri-Philippe


Book ID
125969203
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
269 KB
Volume
61
Category
Article
ISSN
0022-3263

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Asymmetric synthesis of uncommon α-amino
✍ Kiyoshi Tanaka; Mija Ahn; Yukari Watanabe; Kaoru Fuji 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 669 KB

For the purpose of practical preparations of a variety of enantiomerically pure uncommon ¢x-amino acids, alkylations of the chiral glycine equivalent 5, which possesses axially chiral binaphthol as an auxiliary, with several electrophiles were investigated. The alkylation proceeded smoothly in satis