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Asymmetric Synthesis of Rubiginones A2 and C2 and Their 11-Methoxy Regioisomers

✍ Scribed by M. Carmen Carreño; Álvaro Somoza; María Ribagorda; Antonio Urbano


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
254 KB
Volume
13
Category
Article
ISSN
0947-6539

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Synthesis of (2′S)-2′-Deoxy-2′-C-methylp
✍ Gerardo Caballero; Mariana Gallo; Javier M. Montserrat; Adolfo M. Iribarren 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 German ⚖ 154 KB 👁 1 views

We describe the stereoselective synthesis of (2'S)-2'-deoxy-2'-C-methyladenosine ( ) and (2'S)-2'-deoxy-2'-C-methylinosine ( ) as well as their corresponding cyanoethyl phosphoramidites 16 and 19 from 6-O-(2,6dichlorophenyl)inosine as starting material. The methyl group at the 2'-position was introd