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Asymmetric synthesis of (R)-(−)−2-acetyl-1,2,3,4-tetrahydro-2-naphthol: a model study for the synthesis of optically active anthracyclinones

✍ Scribed by Shiro Terashima; Sang-sup Jew; Kenji Koga


Publisher
Elsevier Science
Year
1977
Tongue
French
Weight
269 KB
Volume
18
Category
Article
ISSN
0040-4039

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Stereospecific synthesis of exo-allylic
✍ Mikiko Sodeoka; Takamasa Iimori; Masakatsu Shibasaki 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 264 KB

A method for the stereospecific synthesis of exo-allylic alcohols with trisubstituents is described. Using this methodology in combination with Sharpless catalytic asymmetric epoxidation, an efficient synthesis of (RI-(-)-2-acetyl-5,8-dimethoxy-1,2,3,4tetrahydro-2-naphthol ( 5). an important interme