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Asymmetric synthesis of L-homophenylalanine by equilibrium-shift using recombinant aromatic L-amino acid transaminase

โœ Scribed by Byung-Kwan Cho; Joo-Hyun Seo; Tae-Won Kang; Byung-Gee Kim


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
213 KB
Volume
83
Category
Article
ISSN
0006-3592

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Engineering aromatic L-amino acid transa
โœ Byung-Kwan Cho; Joo-Hyun Seo; Taek-Jin Kang; Juhan Kim; Hyung-Yeon Park; Bon-Su ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 176 KB ๐Ÿ‘ 1 views

An enzymatic asymmetric synthesis was carried out for the preparation of enantiomerically pure L-diphenylalanine using the rationally engineered aromatic L-amino acid transaminase (eAroATEs) obtained from Enterobacter sp. BK2K-1. To rationally redesign the enzyme, structural model was constructed by