The synthesis of an enantiopure isoxazolidine monomer for the incorporation of β(3)-apartic acid residues into β(3)-oligopeptides via chemoselective α-ketoacid-hydroxylamine amide formation. This route involves nitrone cycloaddition of 3-thiophenylpropanal and circumvents limitations of other potent
✦ LIBER ✦
Asymmetric synthesis of enantiopure isoxazolidinone monomers for the synthesis of β3-oligopeptides by chemoselective amide ligation
✍ Scribed by M. Elisa Juarez-Garcia; Shouyun Yu; Jeffrey W. Bode
- Book ID
- 108283289
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 635 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0040-4020
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