Enantioselective synthesis of the Prelog
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Wolfgang Oppolzer; Eric Walther; Carlos Pérez Balado; Jef De Brabander
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Article
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1997
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Elsevier Science
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French
⚖ 258 KB
The group-selective aldolization/desymmetrization of meso dialdehyde 5 with a borylenolate derived from Npropionylbornanesultam ent-2 yields very efficiently lactols 6 with simultaneous generation of four stereogenic centers. Oxidation (6 ---) 7) followed by saponification of the sultam moiety (7 --