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Asymmetric synthesis of densely functionalized 3-substituted 3-hydroxy-β-lactams via novel, highly stereoselective Baylis-Hillman and allylation reactions of enantiopure 3-oxo-2-azetidinones

✍ Scribed by Benito Alcaide; Pedro Almendros; Cristina Aragoncillo

Book ID: 104262308
Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 238 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(99)01527-0

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✦ Synopsis

New asymmetric routes based on both Baylis-Hillman and allylation reactions of enantiopure 3-oxo-2azetidinones are used for the highly stereoselective, efficient preparation of densely functionalized 3-substituted 3-hydroxy-l~-lactams.

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