A practical synthesis of enantiopure eth
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Daqiang Xu; Kapa Prasad; Oljan RepiΔ; Thomas J. Blacklock
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Article
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1997
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Elsevier Science
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English
β 465 KB
A simple and practical method for large scale preparation of optically pure ethyl 2-amino-l-cyclohexanecarboxylate was developed via a reductive amination of 2oxo-cyclohexanecarboxylate with a chiral ot-methylbenzylamine. The major diastereomer was isolated in optically pure form by a simple and eff