Asymmetric synthesis of 3-hydroxyacids from aldehyde or dialkyl ketone
β Scribed by Yoshihiro Kudo; Mamoru Iwasawa; Masayuki Kobayashi; Yasuhisa Senda; Sekio Mitsui
- Book ID
- 104236734
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- French
- Weight
- 104 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
The asymmetric synthesis of 3-hydroxyacids from ketones and acetates by means of diethylaminomagnesium bromide(Et*NMgBr) was applied to the synthesis
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An efficient synthetic procedure for the preparation of a diverse library of 1,3-benzodioxoles was developed by applying controlled microwave heating in comparison with currently available conventional heating. Reactions were completed in less than 3 h. The isolation of product is simple, the isolat
## Abstract An improved protocol is developed which is applicable to largeβscale synthesis.
Trifluoromethylaldehydes and ketones ; tributyl tin hydride ; reduction ; oxidation Abstracts : 4,4,4-Trifluoroacroleines 2 have been converted specifically by tributyl tin hydride to aldehydes 3 or ketones 4, according to the catalyst and conditions employed.