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Asymmetric synthesis of (2R)-2-hydroxy-2-(2(Z)-octenyl)-1-cyclopentanone

✍ Scribed by Iwasaki, Genji; Sano, Mami; Sodeoka, Mikiko; Yoshida, Kiyoshi; Shibasaki, Masakatsu


Book ID
127354034
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
629 KB
Volume
53
Category
Article
ISSN
0022-3263

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## Abstract The synthesis of 2,2‐dimethyl‐ and 2,2‐diphenylcyclopentanone in high yield is reported by the ring expansion of the corresponding 1‐(disubstituted carbinol)‐1‐hydroxycyclobutane in polyphosphoric acid. Modifications of the general synthetic route using reported reactions offers a gener