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Asymmetric synthesis and stereochemistry of chiralcis- andtrans-3-alkyl-4-aminopiperidines

✍ Scribed by G. V. Grishina, E. R. Luk’yanenko, A. A. Borisenko, M. Yu. Antipin


Book ID
118298121
Publisher
Springer US
Year
2012
Tongue
English
Weight
580 KB
Volume
48
Category
Article
ISSN
0009-3122

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## Abstract We report a synthesis of a protected derivative of __trans__‐4‐aminopiperidine‐3‐carboxylic acid (APiC). The route provides either enantiomer. All intermediates are purified by crystallization, and large‐scale preparation is therefore possible. An analogous route provides either enantio