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Asymmetric Synthesis. 32. A New Access to Enantiomerically Pure (S)-(-)-Pipecolic Acid and 2- or 6-Alkylated Derivatives

✍ Scribed by Berrien, J.-F.; Royer, J.; Husson, H.-P.


Book ID
117998488
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
777 KB
Volume
59
Category
Article
ISSN
0022-3263

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Enzymes in organic synthesis, 25. Lipase
✍ Ozegowski, Rüdiger ;Kunath, Annamarie ;Schick, Hans 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 462 KB 👁 1 views

## Abstract The preparation of enantiomerically pure 1‐(2‐methylpropyl) 4‐hydrogen (__S__)‐2‐methylbutanedioate (__ent__‐3) by an enzyme‐catalyzed sequential esterification of (±)‐2‐methylbutanedioic anhydride (__rac__‐1) demands two different enzymes. Lipozyme, a lipase from __Mucor miehei__, was