Asymmetric synthesis. 29. Preparation of 1,8-diazaspiro[5.5]undecane derivatives
β Scribed by Zhu, Jieping; Quirion, Jean Charles; Husson, Henri Philippe
- Book ID
- 120570167
- Publisher
- American Chemical Society
- Year
- 1993
- Tongue
- English
- Weight
- 738 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
A divergent synthesis of 1-and 5-substituted 3,9-diazaspiro[5.5]undecanes and undecan-2-ones is described, in which the key step is an efficient Michael addition of a lithium enolate to a tetrasubstituted olefin acceptor. A variety of substituents (butyl, phenyl, and propoxyl) were introduced at C-1
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract Quick access to polyfunctional spiroketal (3__R__)β4[(2__S__,6__R__,8__R__,10__S__)β4,4βbis(ethylthio)β10βhydroxyβ8β(2βhydroxyethyl)β1,7βdioxaspiro[5.5]undecβ2βyl]butaneβ1,3βdiol [(+)β**19**] is now available through the stereoselective functionalization of enantiomerically pure protect