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Asymmetric Syntheses of New Functionalized β -Amino Alcohols via Diastereoselective Addition of Organometallic Reagents onto Oxazolidines

✍ Scribed by Agami, Claude; Comesse, Sébastien; Kadouri-Puchot, Catherine


Book ID
127205735
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
72 KB
Volume
67
Category
Article
ISSN
0022-3263

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The chiral formylferrocenes 2-5 have been readily prepared in good yields by ortho-lithiation of the TMS-blocked orunblocked aminoferrocenes and subsequent reaction with DMF. The stereochemistry of the reaction of 2 with organometallic reagents has been examined. Reactions of 2 with Grignard and org