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Asymmetric syntheses of both enantiomers of amphetamine hydrochloride via bakers‘ yeast reduction of phenylacetone

✍ Scribed by Shi, Xiao-Xin; Yao, Jian-Zhong; Kang, Li; Shen, Chun-Li; Yi, Fei


Book ID
118070780
Publisher
Science Reviews 2000 Ltd
Year
2004
Tongue
English
Weight
99 KB
Volume
2004
Category
Article
ISSN
0308-2342

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Asymmetric synthesis of both enantiomers
✍ Robert Chênevert; Geneviève Fortier; Rachid Bel Rhlid 📂 Article 📅 1992 🏛 Elsevier Science 🌐 French ⚖ 530 KB

Microbiological reduction of ethyl benxoylscetate by bakers' yeast (Saccharomyces cerevisiae), Beauwria sul@rescens or Geofrichum candidum afforded ethyl (S)-3-hydroxy-3-pheuylpropionate in high optical yield 'this enantiomerically pure alcohol was converted into both onsntiomers of fluoxetine (7).