Studies on novel and chiral 1,4-dihydrop
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Satoshi Obika; Toshihiko Nishiyama; Satoshi Tatematsu; Kazuyuki Miyashita; Takes
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Article
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1997
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Elsevier Science
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French
โ 537 KB
In the reduction of ketones with NADH mimics, (Ss)-l-substituled 3-(p-tolylsulfinyl)-1,4-dihydropyridines 1, the stereospecific transfer of one of the C-4 hydrogens, which is syn to the S-O bond, was experimentally revealed to be involved by employing the 2-methyl derivative 2 and the 4-deuterated d