Applying alpha-phenacyl chloride to the
✍
Yu-gang Shi; Yun Fang; Yue-ping Ren; Hui-lei Guan; Jing-Yang Zhang
📂
Article
📅
2009
🏛
Wiley (John Wiley & Sons)
🌐
English
⚖ 135 KB
## Abstract **BACKGROUND:** The enantioselectivity of reduction of ethyl 2‐oxo‐4‐phenylbutyrate (EOPB) to synthesize ethyl (__R__)‐2‐hydroxy‐4‐phenylbutyrate ((__R__)‐EHPB) catalyzed with baker's yeast in diethyl ether can be improved by the introduction of alpha‐phenacyl chloride (PC). However, th