Asymmetric reduction of acetophenone with chiral polymeric reagents: Supported sodium borohydride on chiral amino-alcohol bound to a polymer

Asymmetric reduction of acetophenone wit

Asymmetric reduction of acetophenone with chiral polymeric reagents: Supported sodium borohydride on chiral quaternary ammonium binded to a polymer

✍ K. Adjidjonou; C. Caze 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 312 KB

We have shown the possibility of enantiomeric induction in the reduction of prochiral ketones by NaBH4 supported on a chiral support. The supports involve polymers (porous or gel type) containing chiral quaternary ammonium groups in the side chain. Two chemical ways were tested to obtain these types