𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Asymmetric reaction of diethylzinc with aldehydes catalyzed by l-menthopyrazole derivatives

✍ Scribed by Choji Kashima; Kohei Higashide; Yohei Miwa; Yoshihiro Tsukamoto

Publisher
Journal of Heterocyclic Chemistry
Year
2002
Tongue
English
Weight
80 KB
Volume
39
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

N‐Hydroxyalkyl‐1‐menthopyrazoles acted as a chiral catalyst for the diethylzinc (1) addition to aromatic aldehydes, and 1‐aryl‐1‐propanols were afforded enantioselectively. These reactions were carried out optimally in toluene at 40 °C in the presence of 30 mol% of (2′S)‐2‐(2‐phenyl‐2‐hydroxyethyl)‐3‐phenyl‐1‐men‐thopyrazole ((S)‐16d) to afford optically active 1‐aryl‐1‐propanols up to 70% ee (S).

📜 SIMILAR VOLUMES

ChemInform Abstract: Asymmetric Borane R
ChemInform Abstract: Asymmetric Borane Reduction of Ketones Catalyzed by N-Hydroxyalkyl-l-menthopyrazoles.
✍ Choji Kashima; Yoshihiro Tsukamoto; Kohei Higashide; Hiroyuki Nakazono 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 29 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v

L-Proline Amide Catalyzed Direct Asymmet
L-Proline Amide Catalyzed Direct Asymmetric Aldol Reaction of Aldehydes with Chloroacetone.
✍ Long He; Zhuo Tang; Lin-Feng Cun; Ai-Qiao Mi; Yao-Zhong Jiang; Liu-Zhu Gong 📂 Article 📅 2006 🏛 John Wiley and Sons ⚖ 27 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.