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Asymmetric Michael Additions via SAMP-/RAMP-Hydrazones Enantioselective 1,4-Addition of Methyl Ketones to Knoevenagel Acceptors1)

โœ Scribed by Enders, Dieter ;Demir, Ayhan S. ;Rendenbach, Beatrice E. M.


Publisher
Wiley (John Wiley & Sons)
Year
1987
Tongue
English
Weight
526 KB
Volume
120
Category
Article
ISSN
0009-2940

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๐Ÿ“œ SIMILAR VOLUMES


Asymmetric michael additions via SAMP/RA
โœ Enders, Dieter ;Wahl, Heiner ;Papadopoulos, Kyriakos ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 979 KB

## Abstract Asymmetric Michael addition of lithiated methyl ketone SAMP hydrazones (S)โ€3 to a variety of alkenylphosphonates (E)โ€2 followed by oxidative cleavage of the 1,4โ€adducts (__S,S__)โ€4 by ozonolysis afforded 2โ€substituted 4โ€oxophosphonates (__S__)โ€5 in usually moderate to very good overall