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Asymmetric Induction in the Replacement of Diastereotopic Bromine Atoms by Lithium Atoms

✍ Scribed by Prof. Dr. Reinhard W. Hoffmann; Dipl.-Chem. Martin Bewersdorf; Dr. Klaus Ditrich; Dipl.-Chem. Michael Krüger; Rainer Stümer


Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
249 KB
Volume
27
Category
Article
ISSN
0044-8249

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✍ Hoffmann, Reinhard W. ;Bewersdorf, Martin ;Kr üger, Michael ;Mikolaiski, Wolfgan 📂 Article 📅 1991 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 999 KB

Bromine-lithium exchange in l,l-dibromo-3-(trimethylsilyl-silylating agents. Diastereoselectivity in the generation and oxy)alkanes 4 and 6 affords the carbenoids 8 and 14, which trapping of the carbenoids ranged between 70 -90% for 8 and have been added to ketones, aldehydes, arylboronates, and >90