Asymmetric activation of chiral titanium(IV) complexes is found to be essential to provide higher levels of enantioselectivity than that attained by enantiopure catalysts in Diels-Alder reactions of the Danishefsky diene and glyoxylate. (~
Asymmetric induction in reactions of styrenes with 1,4-benzoquinones utilizing chiral titanium(IV) complexes
β Scribed by Engler, Thomas A.; Letavic, Michael A.; Reddy, Jayachandra P.
- Book ID
- 126028091
- Publisher
- American Chemical Society
- Year
- 1991
- Tongue
- English
- Weight
- 417 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0002-7863
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π SIMILAR VOLUMES
Good levels of 1,4-syn asymmetric induction are obtained in the TiCl 4 -mediated aldol reaction of methyl a-silyloxy ketones with achiral aldehydes. Such methodology represents a new approach to the substrate-controlled acetate aldol reaction, which can be useful to design more efficient syntheses o
Asymmetric induction in the high pressure (15 kbar, 1.5 GPa) Duels-Alder reactlon of e-benzoqulnone with choral 2,4-pentadienoic acid derivatives is evaluated The reactions afford 4a,5,8,8a-tetrahydro-1,4-naphthalenedlones in up to 50% enantlomenc excess.