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Asymmetric induction in phase transfer catalyzed reactions: a comment on a structural feature of the catalyst

โœ Scribed by John M. McIntosh


Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
119 KB
Volume
20
Category
Article
ISSN
0040-4039

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โœฆ Synopsis


Recently, several groups have expressed interest in employing chiral catalysts in phasetransfer reactions in order to achieve absolute asymmetric syntheses.' The attractiveness of this "pseudo-enzymic" process is obvious. The purpose of this communication is to point out one' factor which does not seem to have been specifically recognized and which bears on the question of catalyst structure.


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Towards phase-transfer catalysts with a
โœ Christabel Carter; Sarah Fletcher; Adam Nelson ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 445 KB

The ability of chiral anions, for example bis[1,1%-bi-2-naphtholato]borate, to induce asymmetry in the reactions of prochiral cations was investigated. Ion-pairing of a borate anion with an aziridinium ion was demonstrated by NMR spectroscopy. The addition of N-methyl indole to an iminium ion (benzy