✦ LIBER ✦
Asymmetric hydrolysis, esterfication catalyzed by esterases from porcine pancreas in the synthesis of both enantiomers of cyclopentanoid building blocks
✍ Scribed by Horst Hemmerle; Hans-Joachim Gais
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 254 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
i. Br. (FRG) Summary: The asymmetric synthesis of the cyclopentanoid building blocks 5 and ent-5 from the easily accessible meso-diacetates 4 and meso-diols 7, resnectivelv bv crude PPL and a carboxvl esterase from crude PPL is described. Enzymatic-esterfication of 8 by crud; PPL gave the cyclohexanoid monoacetate 9, whereas by hydrolysis of 10 the cyclobutenoid monoacetate 11 was obtained.