𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Asymmetric hydrogenation of α-ethylstyrenes catalyzed by chiral ruthenium complexes

✍ Scribed by Grant S Forman; Takeshi Ohkuma; William P Hems; Ryoji Noyori

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
66 KB
Volume
41
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

A combined system of RuCl 2 (R,R)-Me-DuPhos n and t-C 4 H 9 OK catalyzes the asymmetric hydrogenation of a-ethylstyrene derivatives. The reaction proceeds with a substrate to catalyst molar ratio of up to 2600 in 2-propanol at 8 atm and room temperature to give the chiral saturated products in 81-89% ee.

📜 SIMILAR VOLUMES

Catalytic asymmetric hydrogenation of α-
Catalytic asymmetric hydrogenation of α-β-unsaturated ketones using chiral ruthenium hydride complexes.
✍ Viviane Massonneau; Paul Le Maux; Gerard Simonneaux 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 106 KB

Chiral ruthenium hydrides : HRuCl(TRPC)2 and H2Ru(TBPC)2 catalyse the hydrogenation of a-&unsaturated ketones to ketones (e.e. 62 X). Asymmetric hydrogenation of prochiral olefins in the presence of chiral rhodium catalyst 1 is now a useful preparative tool for many a-aminoacids