✦ LIBER ✦
Asymmetric hydrogenation of 3-methyl-fumaric and maleic ester monoaldehydes protected as neph-derived oxazolidines
✍ Scribed by Anna Bernardi; Oliviero Carugo; Alessandra Pasquarello; Atanas Sidjimov; Giovanni Poli
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 457 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
✦ Synopsis
The hydrogenanon of 3-methyl-fmru: and malerc ester mono aldehy&s protected as oxazoluims of nor-ephednne (NEPH) denvatwn has been studted Thts transfonnanon takes place with moderate to good rr-jbce stereodtfferenttatton and allows the preparanon of non-racemtc 3-methyl-succutaldehydrc acid methyl ester (1, R=Me) The factors dmatmg the dmstereocontrol are drscussed