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Asymmetric hydrogenation of 2-benzamido(acetamido)-3-(2-thienyl)-2-propenoic acids catalyzed by rhodium-diop complexes

✍ Scribed by C. Cativiela; J. Fernandez; J.A. Mayoral; E. Melendez; R. Uson; L.A. Oro; M.J. Fernandez


Publisher
Elsevier Science
Year
1982
Weight
381 KB
Volume
16
Category
Article
ISSN
0304-5102

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Catalytic asymmetric hydrogenation of 1-
✍ Ryoichi Kuwano; Daisuke Karube; Yoshihiko Ito πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 289 KB

A rhodium complex coordinated with a trans-chelating chiral diphosphine (S,S)-(R,R)-PhTRAP was an effective catalyst for asymmetric hydrogenation of N-acyl-1-aza-2-cycloalkene-2-carboxylates, which gave the corresponding protected cyclic or-amino acids with 73-97% ee.