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Asymmetric Hydroformylation of Vinyl Acetate: Application in the Synthesis of Optically Active Isoxazolines and Imidazoles

โœ Scribed by Thomas, P. J.; Axtell, Alex T.; Klosin, Jerzy; Peng, Wei; Rand, Cynthia L.; Clark, Thomas P.; Landis, Clark R.; Abboud, Khalil A.


Book ID
121407357
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
144 KB
Volume
9
Category
Article
ISSN
1523-7060

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The first rigid and sterically regular chiral poly[2,2 -bis(diphenylphosphino)-1,1 -binaphthyl] [poly(BINAP)] is synthesized. The application of this polymer ligand in asymmetric hydrogenations is examined. High enantioselectivity for the asymmetric hydrogenation of ketones is achieved. The catalyti