Asymmetric Functionalization of C-H Bonds

✍ Scribed by Shu-Li You, Chris Hardacre

Publisher: The Royal Society of Chemistry
Year: 2015
Tongue: English
Leaves: 430
Series: RSC catalysis series no. 25
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

Asymmetric C-H direct functionalization reactions are one of the most active and fascinating areas of research in organic chemistry due to their significance in the construction of molecular complexity without pre-activation, and the step economy and atom economy features in potential synthetic application. Distinguishing the reactivity among numerous C–H bonds in one single molecule represents one of the most challenging issues in organic synthesis and requires precise reaction design. As such, this field is now receiving increasing attention from researchers.

This book provides the first comprehensive review of this field, summarizing the origin, mechanism, scope and applications of the asymmetric C-H bond functionalization reaction. It covers organocatalytic reactions and transition-metal-catalyzed reactions, as well as asymmetric C-H functionalization reactions not described in other books.

Written by a leading expert in this field, the book is ideal for postgraduates and researchers working in organic synthesis, catalysis, and organometallic chemistry.

✦ Table of Contents

Content: Asymmetric C-H Bond Insertion Reactions / Wen-Ting Wu, Ze-Peng Yang and Shu-Li You --
Asymmetric Cross-Dehydrogenative Coupling (CDC) Reactions / Shou-Guo Wang and Shu-Li You --
Asymmetric Oxidative Biaryl Coupling Reactions / Chao Zheng and Shu-Li You --
Asymmetric [1,5]-Hydride Transfer Reactions / Xiao-Wei Liang, Chao Zheng and Shu-Li You --
Asymmetric Functionalization of C-H Bonds via a Transient Carbon-Metal (C-M) Species / De-Wei Gao, Jun Zheng, Ke-Yin Ye, Chao Zheng and Shu-Li You --
Asymmetric Friedel-Crafts Alkylation Reactions / Qiang Kang and Shu-Li You --
N-Heterocyclic Carbene-Catalyzed Asymmetric Functionalization of Aldehyde C-H Bonds / Yi Li and Shu-Li You --
Asymmetric Hydroacylation Reactions / Qing-Long Xu and Shu-Li You --
Asymmetric Hydrovinylation Reactions / Qing-Long Xu and Shu-Li You.

✦ Subjects

Carbon compounds. Hydrogen bonding. Catalysis.

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