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Asymmetric Friedel—Crafts Reaction of Indoles with Imines by an Organic Catalyst.

✍ Scribed by Yong-Qiang Wang; Jun Song; Ran Hong; Hongming Li; Li Deng

Publisher
John Wiley and Sons
Year
2006
Weight
32 KB
Volume
37
Category
Article
ISSN
0931-7597

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Asymmetric Organocatalytic Aza-Friedel–Crafts Reaction of Naphthols with N-Sulfonyl Imines
✍ Pankaj Chauhan; Swapandeep Singh Chimni 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 434 KB 👁 1 views

## Abstract The first organocatalytic asymmetric aza‐Friedel–Crafts reaction of naphthols with __N__‐sulfonyl imines has been developed. The cupreine‐derived bifunctional organocatalyst BzCPN efficiently catalyzes the formation of aza‐Friedel–Crafts products in good to excellent yields (up to 99 %)