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Asymmetric epoxidation of hydrocarbon olefins by tert-butyl hydroperoxide with molybdenum(VI) catalysts in the presence of optically active diols. Application to the asymmetric synthesis of (3S)-2,3-oxidosqualene

✍ Scribed by Kazuhide Tani; Masayoshi Hanafusa; Sei Otsuka


Publisher
Elsevier Science
Year
1979
Tongue
French
Weight
209 KB
Volume
20
Category
Article
ISSN
0040-4039

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✦ Synopsis


Catalytic enantioselective epoxidation of prochiral olefins without functional groups was achieved by tert-BuOOH using Mo(0)2(acac)2 -optically active diols as catalysts. In spite of dramatic developements in asymmetric hydrogenations using optically active transition metal catalysts during recent years', little has been achieved in the field of asymmetric oxidations with chiral transition metal catalysts.