Asymmetric epoxidation of digeranyl by cultured cells of Nicotiana tabacum

✍ Scribed by Osamu Nakagawa; Kei Shimoda; Sunsuke Izumi; Toshifumi Hirata

• Publisher: John Wiley and Sons
• Year: 2003
• Tongue: French
• Weight: 99 KB
• Volume: 46
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.681

✦ Synopsis

Abstract

Asymmetric epoxidation of digeranyl, which is a squalene analog, with cultured cells of Nicotiana tabacum was investigated. Feeding of [8‐^3^H]‐digeranyl into the cultured cells of N. tabacum resulted in the formation of (3__S__)‐2,3‐epoxydigeranyl and 6,7‐epoxydigeranyl. It was found that the epoxidation of digeranyl with N. tabacum was highly stereoselective. Copyright © 2003 John Wiley & Sons, Ltd.